Self-repairing machines would change maintenance, manufacturing and exploration, but only if they could reliably detect damage and obtain replacement material.
What changes first
A genuinely self-repairing robot would need sensors, diagnosis, replacement materials and precise manipulation. It would reduce some maintenance costs, but it would not eliminate failure because complex systems can suffer damage beyond their repair capabilities.
The physical or biological constraint
The scenario should be treated as a thought experiment. Where the consequences depend on unknown parameters, there is no single precise outcome.